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health · HHS-NIH11

Notice of Intent to Publish a Funding Opportunity Announcement for Trailblazer Award for New and Early-Stage Investigators (R21 Clinical Trial Optional)

National Institutes of Health · FOR-EB-26-001

Closed

Deadline

TBD

GRANTQUICK SUMMARYPlain-English Overview

Notice of Intent to Publish a Funding Opportunity Announcement for Trailblazer Award for New and Early-Stage Investigators (R21 Clinical Trial Optional). National Institutes of Health. The National Institute of Biomedical Imaging and Bioengineering, with the National Eye Institute, the National Institute on Aging, the National Cancer Institute, and the National Center for Complementary and Integrative Health intend to publish a Notice of... Funding amounts not specified.

Who Should Apply

Small businesses, Other Native American Tribal Organizations, Independent school districts, Federally Recognized Native American Tribal Governments, State governments (+6 more)

Who Should NOT Apply

Organizations not matching the eligible applicant types listed above

Key Requirements (Plain English)

  • See full opportunity listing for requirements

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Focus your proposal on clear outcomes, alignment with agency priorities, and demonstrate organizational capacity.

Competitiveness: Moderate to high — federal grants are always competitive

What This Grant Funds

The National Institute of Biomedical Imaging and Bioengineering, with the National Eye Institute, the National Institute on Aging, the National Cancer Institute, and the National Center for Complementary and Integrative Health intend to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the Trailblazer Award. This is an opportunity for NIH-defined New and Early Stage Investigators (https://grants.nih.gov/policy/early-investigators/index.htm) to pursue research programs that integrate engineering and the physical sciences with the life and/or biomedical sciences. A Trailblazer project may be exploratory, developmental, proof of concept, or high-risk high-impact, and may be technology design-directed, discovery-driven, or hypothesis-driven. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the R21 activity code. Investigators with expertise and insights into the application of principles and techniques from engineering and quantitative sciences, such as physics, mathematics, chemistry, and computer sciences are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in trans-disciplinary research approaches with the potential to open new areas of biomedical investigation will be encouraged and these investigators should also begin considering applying for this application. 

Who Can Apply

Eligible Applicant Types

Small BusinessesOther Tribal OrganizationsIndependent School DistrictsFederally Recognized Tribal GovernmentsState Governments501(c)(3) NonprofitsCounty GovernmentsPublic And Indian Housing AuthoritiesPublic Colleges & UniversitiesPrivate Colleges & UniversitiesFor-Profit Organizations

Funding Details

Cost Sharing Required?
No
Funding Instrument
grant

Key Dates

Posted: June 11, 2025
Application Deadline: TBD (0 days remaining)

Agency Contact

Randy King National Institute of Biomedical Imaging and Bioengineering (NIBIB) 301-451-0707

Randy.King@nih.gov

Ready to apply?

View the full NOFO and submit your application on Grants.gov