health · HHS-NIH11

Avant Garde/Avenir Awards for Investigators Conducting High Risk/High Reward Research on HIV and Substance Use (or Substance Use Disorders) (DP1 Clinical Trial Optional)

National Institutes of Health · PAR-27-026

776 days left

Deadline

September 25, 2028

GRANTQUICK SUMMARYPlain-English Overview

Avant Garde/Avenir Awards for Investigators Conducting High Risk/High Reward Research on HIV and Substance Use (or Substance Use Disorders) (DP1 Clinical Trial Optional). National Institutes of Health. The purpose of this notice of funding opportunity (NOFO) is to support innovative basic, clinical, translational, and implementation science research relevant to HIV and substance use. This initiative encourages high risk high impact transformative studies that advance knowledge and strategies for... Funding amounts not specified.

Who Should Apply

Other Native American Tribal Organizations, City/township governments, Federally Recognized Native American Tribal Governments, Private universities/colleges, Public And Indian Housing Authorities (+10 more)

Who Should NOT Apply

Organizations not matching the eligible applicant types listed above

Key Requirements (Plain English)

•Refer to Section III
•Deadline: 2028-09-25

💡 GrantQuick Tip

Focus your proposal on clear outcomes, alignment with agency priorities, and demonstrate organizational capacity.

Competitiveness: Moderate to high — federal grants are always competitive

What This Grant Funds

The purpose of this notice of funding opportunity (NOFO) is to support innovative basic, clinical, translational, and implementation science research relevant to HIV and substance use. This initiative encourages high risk high impact transformative studies that advance knowledge and strategies for HIV prevention, diagnosis, treatment and virus suppression in people who use substances and/or have a substance use disorder.

Attachments

PDF

PAR-27-026-Full-Announcement.html

Who Can Apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Eligible Applicant Types

Other Tribal OrganizationsCity/Township GovernmentsFederally Recognized Tribal GovernmentsPrivate Colleges & UniversitiesPublic And Indian Housing AuthoritiesPublic Colleges & UniversitiesOther (see NOFO for details)State GovernmentsNonprofits without 501(c)(3)501(c)(3) NonprofitsSmall BusinessesFor-Profit OrganizationsCounty GovernmentsSpecial District GovernmentsIndependent School Districts

Funding Details

Cost Sharing Required?: No
Funding Instrument: grant

Key Dates

Posted: June 9, 2026

Application Deadline: September 25, 2028 (776 days remaining)

Agency Contact

nidagmbemail@nida.nih.gov nidagmbemail@nida.nih.gov

nidagmbemail@nida.nih.gov

Ready to apply?

View the full NOFO and submit your application on Grants.gov

View on Grants.gov