health · HHS-NIH11

GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed)

National Institutes of Health · RFA-HG-27-011

67 days left

Award Range

$0 – $1.3M

Total Program Funding

$2.0M

Expected Awards

Deadline

October 30, 2026

GRANTQUICK SUMMARYPlain-English Overview

NIH is funding one $1.25M award for the GREGoRi Data Coordination and Outreach Center — the data management hub for the entire GREGoRi rare disease genomics consortium. This center manages genomic/phenotypic data across all consortium sites, ensures data sharing, provides bioinformatics infrastructure, and conducts outreach to rare disease communities. No clinical trials.

Who Should Apply

Research institutions with large-scale genomic data management infrastructure, bioinformatics expertise, and experience coordinating multi-site research consortia. Must have rare disease community engagement capacity.

Who Should NOT Apply

Individual research labs, institutions without consortium coordination experience, or groups without both data management AND community outreach capabilities.

Key Requirements (Plain English)

•Must manage data coordination for the GREGoRi consortium
•Must provide bioinformatics infrastructure for genomic/phenotypic data
•Must conduct outreach to rare disease communities
•Single award up to $1.25M
•No clinical trials
•No cost-sharing required

💡 GrantQuick Tip

Data coordination centers for NIH consortia go to institutions with proven track records of managing multi-site genomic data — think dbGaP-experienced groups, ClinGen contributors, or organizations running other rare disease data platforms (UDN, CMGs). You need both technical infrastructure (secure data sharing, variant databases) AND rare disease community engagement experience.

Competitiveness: Very high — single award for a consortium-level data center. Only institutions with existing genomic data management platforms are competitive.

What This Grant Funds

The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of Funding Opportunity is to establish the GREGoRi Data Coordination and Outreach Center. The Data Coordination and Outreach Center will act as the central point of coordination for the GREGoRi Research Program, and will be responsible for ensuring that the protocols, data, metadata, computational tools and other resources developed as part of GREGoRi are made available to the broader research community.

Attachments

PDF

RFA-HG-27-011-Full-Announcement.html

Who Can Apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Eligible Applicant Types

County GovernmentsSpecial District GovernmentsPrivate Colleges & UniversitiesFederally Recognized Tribal GovernmentsOther Tribal OrganizationsPublic Colleges & UniversitiesOther (see NOFO for details)State GovernmentsCity/Township Governments501(c)(3) NonprofitsIndependent School DistrictsNonprofits without 501(c)(3)Public And Indian Housing AuthoritiesSmall BusinessesFor-Profit Organizations

Funding Details

Maximum Award: $1.3M
Total Program Funding: $2.0M
Expected Number of Awards: 1
Cost Sharing Required?: No
Funding Instrument: cooperative_agreement

Key Dates

Posted: June 18, 2026

Application Deadline: October 30, 2026 (67 days remaining)

Agency Contact

GREGoRi Program Team nhgri-gregor@mail.nih.gov

nhgri-gregor@mail.nih.gov

Ready to apply?

View the full NOFO and submit your application on Grants.gov

View on Grants.gov