health · HHS-NIH11

Limited Competition: Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional)

National Institutes of Health · RFA-ES-27-004

776 days left

Award Range

$0 – $1.8M

Total Program Funding

$22.0M

Expected Awards

Deadline

September 25, 2028

GRANTQUICK SUMMARYPlain-English Overview

NIH limited competition for Superfund Hazardous Substances research — 10 grants (up to $1.75M each) for research on health effects of toxic waste sites. Rolling through 2028.

Who Should Apply

Environmental health researchers studying contamination from Superfund sites — exposure assessment, health outcomes, remediation effectiveness.

Who Should NOT Apply

Researchers without toxic substances expertise, non-environmental health investigators.

Key Requirements (Plain English)

•Must study Superfund-related health effects
•10 awards up to $1.75M
•Limited competition
•Rolling through 2028

💡 GrantQuick Tip

Strong program for environmental health researchers near Superfund sites. Propose community-engaged research addressing specific contaminants (PFAS, heavy metals, solvents) at identified sites.

Competitiveness: Moderate — 10 awards for environmental health researchers.

What This Grant Funds

The National Institute of Environmental Health Sciences (NIEHS) is announcing the continuation of the Superfund Hazardous Substance Research and Training Program, referred to as Superfund Research Program (SRP) Centers. SRP Center grants will support problem-based, solution-oriented research Centers that consist of multiple, integrated projects representing both the biomedical and environmental science and engineering disciplines; as well as cores tasked with administrative (which includes Center leadership, data management, and training); translational research and engagement; and research support functions. The scope of the SRP Centers is taken directly from the Superfund Amendments and Reauthorization Act of 1986, which limits competition for this program to accredited institutes of higher education.Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

Attachments

PDF

RFA-ES-27-004-Full-Announcement.html

Who Can Apply

Based on 42 USC 9660(a)(3) eligible applicants are limited to accredited institutes of higher education. Eligible applicants are permitted under the law, and encouraged by NIEHS, to subcontract as appropriate with other organizations as necessary to conduct portions of the research. Examples of other organizations may include generators of hazardous wastes; persons involved in the detection, assessment, evaluation, and treatment of hazardous substances; owners and operators of facilities at which hazardous substances are located; and/or State and local governments. Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Eligible Applicant Types

Private Colleges & UniversitiesPublic Colleges & Universities

Funding Details

Maximum Award: $1.8M
Total Program Funding: $22.0M
Expected Number of Awards: 10
Cost Sharing Required?: No
Funding Instrument: grant

Key Dates

Posted: May 19, 2026

Application Deadline: September 25, 2028 (776 days remaining)

Agency Contact

Hazardous Substances Research Branch National Institute of Environmental Health Sciences NOFO.Information@niehs.nih.gov

National Institute of Environmental Health Sciences NOFO.Information@niehs.nih.gov

Ready to apply?

View the full NOFO and submit your application on Grants.gov

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