health · HHS-NIH11

SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)

National Institutes of Health · PAR-27-098

954 days left

Deadline

April 5, 2029

GRANTQUICK SUMMARYPlain-English Overview

SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional). National Institutes of Health. The Commercialization Readiness Pilot (CRP) program helps small business concerns (SBCs) move NIH-funded SBIR or STTR projects from late-stage development to commercialization. The CRP supports later-stage research and development (R&D) and/or technical assistance that Phase II and Phase IIB... Funding amounts not specified.

Who Should Apply

Independent school districts, Private universities/colleges, City/township governments, Federally Recognized Native American Tribal Governments, Nonprofits (non-501c3) (+10 more)

Who Should NOT Apply

Organizations not matching the eligible applicant types listed above

Key Requirements (Plain English)

•Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir
•Deadline: 2029-04-05

💡 GrantQuick Tip

Focus your proposal on clear outcomes, alignment with agency priorities, and demonstrate organizational capacity.

Competitiveness: Moderate to high — federal grants are always competitive

What This Grant Funds

The Commercialization Readiness Pilot (CRP) program helps small business concerns (SBCs) move NIH-funded SBIR or STTR projects from late-stage development to commercialization. The CRP supports later-stage research and development (R&D) and/or technical assistance that Phase II and Phase IIB Strategic Breakthrough awards do not typically support. This includes:Independent replication or confirmation of key studiesIND- or IDE-enabling studiesClinical studiesManufacturing scale-up and related quality activitiesRegulatory and other specialized technical supportSBCs may subcontract (outsource) a significant amount of the work in a CRP to meet the project goals.

Attachments

PDF

PAR-27-098-Revised-Full-Announcement.html

Who Can Apply

Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity.Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Unfunded international collaborations or unfunded foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

Eligible Applicant Types

Independent School DistrictsPrivate Colleges & UniversitiesCity/Township GovernmentsFederally Recognized Tribal GovernmentsNonprofits without 501(c)(3)Small BusinessesOther Tribal OrganizationsCounty GovernmentsPublic Colleges & UniversitiesSpecial District GovernmentsFor-Profit OrganizationsState Governments501(c)(3) NonprofitsOther (see NOFO for details)Public And Indian Housing Authorities

Funding Details

Cost Sharing Required?: No
Funding Instrument: grant

Key Dates

Posted: May 28, 2026

Application Deadline: April 5, 2029 (954 days remaining)

Agency Contact

NIH SEED (Small business Education and Entrepreneurial Development) SEEDinfo@nih.gov

SEEDinfo@nih.gov

Ready to apply?

View the full NOFO and submit your application on Grants.gov

View on Grants.gov