health · HHS-NIH11

Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)

National Institutes of Health · RFA-CA-27-019

422 days left

Award Range

$50K – $300K

Total Program Funding

$2.4M

Expected Awards

Deadline

October 19, 2027

GRANTQUICK SUMMARYPlain-English Overview

NIH funds 5 grants (up to $300K each) for early-stage development of biomedical informatics technologies — building new software tools, algorithms, or databases from concept to prototype.

Who Should Apply

Researchers developing new bioinformatics/computational tools for biomedical research. Early-stage (prototype/proof-of-concept).

Who Should NOT Apply

Groups maintaining existing tools, researchers without informatics development expertise.

Key Requirements (Plain English)

•Must develop new informatics tools
•5 awards up to $300K
•Must be early-stage/prototype
•Rolling through 2027

💡 GrantQuick Tip

At $300K, develop a working prototype that other researchers can test. Show the unmet need: what can't researchers do today that your tool enables?

Competitiveness: Moderate — 5 awards for new informatics tools with rolling deadline.

What This Grant Funds

This Notice of Funding Opportunity (NOFO) solicits applications for the development of enabling informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this NOFO is focused on early-stage development from prototyping to initial dissemination. Early-stage development is defined for the purpose of this NOFO as initial tool development or the significant modification of existing tools for new applications. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, proposed development plans must have a clear rationale for why the proposed technology is needed and how it will benefit the cancer research field. In addition, mechanisms to solicit feedback from driving research projects and other users throughout the development process must be included.This NOFO encourages applications that involve the development of new, user-friendly informatics technologies that support a wide range of cancer research, including discovery biology, population studies, as well as clinical and translational research. The emphasis is on uniqueness and potential impact on cancer research. In addition, all projects proposed in response to this NOFO must involve the following general attributes:Potential to advance driving cancer research projects and the cancer research field in generalNovel informatics capabilities for the targeted cancer research domainCompelling plans and processes for engaging end users to evaluate and apply the tool or resourceA realistic timeline and milestones for technology development

Attachments

PDF

RFA-CA-27-019-Full-Announcement.html

Who Can Apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Eligible Applicant Types

County GovernmentsIndependent School DistrictsFederally Recognized Tribal GovernmentsSmall BusinessesOther (see NOFO for details)For-Profit OrganizationsSpecial District Governments501(c)(3) NonprofitsCity/Township GovernmentsOther Tribal OrganizationsNonprofits without 501(c)(3)Public Colleges & UniversitiesPublic And Indian Housing AuthoritiesPrivate Colleges & UniversitiesState Governments

Funding Details

Minimum Award: $50K
Maximum Award: $300K
Total Program Funding: $2.4M
Expected Number of Awards: 5
Cost Sharing Required?: No
Funding Instrument: cooperative_agreement

Key Dates

Posted: May 21, 2026

Application Deadline: October 19, 2027 (422 days remaining)

Agency Contact

Center for Strategic Scientific Initiatives (CSSI) nciitcr@mail.nih.gov

nciitcr@mail.nih.gov

Ready to apply?

View the full NOFO and submit your application on Grants.gov

View on Grants.gov