health · HHS-NIH11

Causal Hypotheses on the Oral-Systemic Health Impacts of Human Behaviors among People with Chronic Conditions (U01 Clinical Trial Not Allowed)

National Institutes of Health · PAR-27-057

1044 days left

Award Range

$0 – $500K

Deadline

July 5, 2029

GRANTQUICK SUMMARYPlain-English Overview

Causal Hypotheses on the Oral-Systemic Health Impacts of Human Behaviors among People with Chronic Conditions (U01 Clinical Trial Not Allowed). National Institutes of Health. This Notice of Funding Opportunity (NOFO) invites applications for innovative research on the factors that cause human behaviors and the oral-systemic health impacts of those behaviors to enhance health, lengthen life, and reduce illness and disability among people with chronic conditions. Causal... up to $500,000 per award.

Who Should Apply

State governments, Other Native American Tribal Organizations, Nonprofits (non-501c3), Nonprofits (501c3), Public universities/colleges (+10 more)

Who Should NOT Apply

Organizations not matching the eligible applicant types listed above

Key Requirements (Plain English)

•Refer to Section III
•Deadline: 2029-07-05

💡 GrantQuick Tip

Focus your proposal on clear outcomes, alignment with agency priorities, and demonstrate organizational capacity.

Competitiveness: Moderate to high — federal grants are always competitive

What This Grant Funds

This Notice of Funding Opportunity (NOFO) invites applications for innovative research on the factors that cause human behaviors and the oral-systemic health impacts of those behaviors to enhance health, lengthen life, and reduce illness and disability among people with chronic conditions. Causal hypotheses may include biological, biopsychosocial, congenital, environmental, interpersonal, neurological, psychological, and comorbidity factors that individually, sequentially, or in combination trigger human behaviors and oral-systemic health outcomes, with impacts that may be direct or traceably distal. Applications that propose projects to develop or refine causal hypotheses also are encouraged.

Attachments

PDF

PAR-27-057-Full-Announcement.html

Who Can Apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Eligible Applicant Types

State GovernmentsOther Tribal OrganizationsNonprofits without 501(c)(3)501(c)(3) NonprofitsPublic Colleges & UniversitiesCity/Township GovernmentsFederally Recognized Tribal GovernmentsPublic And Indian Housing AuthoritiesSpecial District GovernmentsCounty GovernmentsFor-Profit OrganizationsSmall BusinessesOther (see NOFO for details)Independent School DistrictsPrivate Colleges & Universities

Funding Details

Maximum Award: $500K
Cost Sharing Required?: No
Funding Instrument: cooperative_agreement

Key Dates

Posted: June 4, 2026

Application Deadline: July 5, 2029 (1044 days remaining)

Agency Contact

National Institute of Dental and Craniofacial Research (NIDCR) deeranotifications@nidcr.nih.gov

deeranotifications@nidcr.nih.gov

Ready to apply?

View the full NOFO and submit your application on Grants.gov

View on Grants.gov