health · HHS-NIH11

Interdisciplinary Research to Understand the Complex Biology of Resilience to Alzheimer’s and Related Dementias Disease Risk

National Institutes of Health · PAR-26-067

Closed

Deadline

TBD

GRANTQUICK SUMMARYPlain-English Overview

Interdisciplinary Research to Understand the Complex Biology of Resilience to Alzheimer’s and Related Dementias Disease Risk. National Institutes of Health. The National Institute on Aging (NIA) intends to publish a Notice of Funding Opportunity (NOFO) that builds upon its investment in data-driven approaches for the purpose of defining molecular mechanisms of resilience in the presence of various types of Alzheimer's disease (AD) and AD-related... Funding amounts not specified.

Who Should Apply

City/township governments, County governments, Independent school districts, Special district governments, Federally Recognized Native American Tribal Governments (+10 more)

Who Should NOT Apply

Organizations not matching the eligible applicant types listed above

Key Requirements (Plain English)

•Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U

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Competitiveness: Moderate to high — federal grants are always competitive

What This Grant Funds

The National Institute on Aging (NIA) intends to publish a Notice of Funding Opportunity (NOFO) that builds upon its investment in data-driven approaches for the purpose of defining molecular mechanisms of resilience in the presence of various types of Alzheimer's disease (AD) and AD-related dementias (ADRD) risk. The goal of this NOFO is to build a robust program that integrates epidemiologic, genomic, and mechanistic research through the use of data driven, systems-based approaches (including the use of artificial intelligence and/or machine learning methods) to discover the molecular/cellular determinants of resilience to AD/ADRD risk across representative populations. The initiative will support the generation of high-dimensional molecular data from brain and peripheral tissues, including longitudinal data, to enable dynamic modeling of resilience mechanisms and to discover molecular predictors of resilience.

Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO intends to utilize the U01 activity code. Investigators with expertise and insights into this area of aging research are encouraged to begin to consider applying for this new NOFO.

Who Can Apply

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Eligible Applicant Types

City/Township GovernmentsCounty GovernmentsIndependent School DistrictsSpecial District GovernmentsFederally Recognized Tribal GovernmentsNonprofits without 501(c)(3)Public Colleges & UniversitiesOther Tribal OrganizationsPublic And Indian Housing AuthoritiesFor-Profit Organizations501(c)(3) NonprofitsSmall BusinessesOther (see NOFO for details)State GovernmentsPrivate Colleges & Universities

Funding Details

Cost Sharing Required?: No
Funding Instrument: cooperative_agreement

Key Dates

Posted: September 3, 2025

Application Deadline: TBD (0 days remaining)

Agency Contact

Suzana Petanceska, Ph.D. 301-496-9350

petanceskas@nia.nih.gov

Ready to apply?

View the full NOFO and submit your application on Grants.gov

View on Grants.gov