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health · HHS-NIH11

Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research (P50 Clinical Trial Optional)

National Institutes of Health · PAR-27-127

595 days left

Deadline

May 25, 2028

GRANTQUICK SUMMARYPlain-English Overview

Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research. National Institutes of Health. The National Institute of Mental Health (NIMH) seeks research applications for the Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research. Primary research objectives include 1) advancing the state of science in basic brain and behavior research to uncover and... up to $2,000,000 per award.

Who Should Apply

Special district governments, For-profit organizations, Nonprofits (501c3), Nonprofits (non-501c3), Federally Recognized Native American Tribal Governments (+8 more)

Who Should NOT Apply

Organizations not matching the eligible applicant types listed above

Key Requirements (Plain English)

  • •Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U

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Focus your proposal on clear outcomes, alignment with agency priorities, and demonstrate organizational capacity.

Competitiveness: Moderate to high — federal grants are always competitive

What This Grant Funds

This notice of funding opportunity (NOFO) encourages applications for Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research. The National Institute of Mental Health (NIMH) seeks teams of integrative researchers working at different levels of analysis and employing novel, and creative experimental approaches to address high-risk, high-impact questions with the primary objectives of: (a) advancing basic brain and behavior research that will uncover underlying mechanisms that could provide the foundation for understanding mental disorders; (b) supporting the integration and translation of basic and clinical neuroscience research on severe mental illnesses; (c) advancing our understanding of the neurobehavioral mechanisms and trajectories of psychopathology that begin in development. This program is intended only for projects that could not be achieved using other, more standard grant mechanisms.

Attachments

Who Can Apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Eligible Applicant Types

Nonprofits without 501(c)(3)501(c)(3) NonprofitsCounty GovernmentsPublic And Indian Housing AuthoritiesSmall BusinessesSpecial District GovernmentsFederally Recognized Tribal GovernmentsPrivate Colleges & UniversitiesFor-Profit OrganizationsOther (see NOFO for details)City/Township GovernmentsState GovernmentsPublic Colleges & UniversitiesIndependent School DistrictsOther Tribal Organizations

Funding Details

Cost Sharing Required?
No
Funding Instrument
grant

Key Dates

Posted: September 1, 2026
Application Deadline: May 25, 2028 (595 days remaining)

Agency Contact

Division of Neuroscience and Basic Behavioral Science (DNBBS) DNBBSinitiatives@mail.nih.gov

DNBBSinitiatives@mail.nih.gov

Ready to apply?

View the full NOFO and submit your application on Grants.gov