health · HHS-NIH11

NextTech: Translational Development of Next-Generation Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed)

National Institutes of Health · RFA-EB-26-004

Closed

Total Program Funding

$6.0M

Expected Awards

Deadline

TBD

GRANTQUICK SUMMARYPlain-English Overview

NextTech: Translational Development of Next-Generation Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed). National Institutes of Health. This Notice of Funding Opportunity (NOFO) is to encourage applications from investigators to advance the development and translation of next-generation technologies to prevent, monitor, diagnose, and treat disorders within the missions of the NIH Brain Research through Advancing Innovative... $6,000,000 total program funding; ~4 awards expected.

Who Should Apply

Small businesses, For-profit organizations, Federally Recognized Native American Tribal Governments, Public universities/colleges, City/township governments (+10 more)

Who Should NOT Apply

Organizations not matching the eligible applicant types listed above

Key Requirements (Plain English)

•Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U

💡 GrantQuick Tip

High-value award — invest significantly in proposal quality. Consider hiring a grant writer.

Competitiveness: Very high — extremely limited awards available

What This Grant Funds

This Notice of Funding Opportunity (NOFO) is to encourage applications from investigators to advance the development and translation of next-generation technologies to prevent, monitor, diagnose, and treat disorders within the missions of the NIH Brain Research through Advancing Innovative Neurotechnologies (BRAIN) and The Helping to End Addiction Long-term (HEAL) Initiatives. Awarded activities will facilitate the translation of new devices up to the stage of readiness for first in human (FIH) clinical trials by overcoming key challenges identified during preliminary proof-of-concept studies. The scope of the program includes technology development and optimization, and studies to prepare for approvals for human use.

Who Can Apply

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Eligible Applicant Types

Small BusinessesFor-Profit OrganizationsFederally Recognized Tribal GovernmentsPublic Colleges & UniversitiesCity/Township Governments501(c)(3) NonprofitsState GovernmentsOther Tribal OrganizationsNonprofits without 501(c)(3)Special District GovernmentsPrivate Colleges & UniversitiesIndependent School DistrictsPublic And Indian Housing AuthoritiesCounty GovernmentsOther (see NOFO for details)

Funding Details

Total Program Funding: $6.0M
Expected Number of Awards: 4
Cost Sharing Required?: No
Funding Instrument: grant

Key Dates

Posted: February 27, 2026

Application Deadline: TBD (0 days remaining)

Agency Contact

NIBIB Program Officers for RFA-EB-26-004 Please contact via e-mail.

NIBIB_Devices@NIH.gov

Ready to apply?

View the full NOFO and submit your application on Grants.gov

View on Grants.gov