health · HHS-NIH11

Exploratory Clinical Neuroscience Research on Substance Use Disorders

National Institutes of Health · PAR-26-093

Closed

Expected Awards

Deadline

TBD

GRANTQUICK SUMMARYPlain-English Overview

Exploratory Clinical Neuroscience Research on Substance Use Disorders. National Institutes of Health. This Notice of Funding Opportunity (NOFO) uses a R61/R33 Phased Innovation Award mechanism to support clinical research applications that are exploratory and developmental in nature and focus on understanding the neurobiological mechanisms underlying SUD, including fundamental brain function... ~6 awards expected.

Who Should Apply

State governments, Public And Indian Housing Authorities, Other Native American Tribal Organizations, Small businesses, City/township governments (+10 more)

Who Should NOT Apply

Organizations not matching the eligible applicant types listed above

Key Requirements (Plain English)

•Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U

💡 GrantQuick Tip

Focus your proposal on clear outcomes, alignment with agency priorities, and demonstrate organizational capacity.

Competitiveness: High — limited number of awards

What This Grant Funds

This Notice of Funding Opportunity (NOFO) uses a R61/R33 Phased Innovation Award mechanism to support clinical research applications that are exploratory and developmental in nature and focus on understanding the neurobiological mechanisms underlying SUD, including fundamental brain function relevant to substance use. This NOFO is particularly designed to support exploratory/developmental projects requiring budgets that would exceed that allowed for the R21 mechanism (Neuroscience Research on Drug Abuse (R21 Clinical Trial Optional)

Who Can Apply

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Eligible Applicant Types

State GovernmentsPublic And Indian Housing AuthoritiesOther Tribal OrganizationsSmall BusinessesCity/Township GovernmentsFederally Recognized Tribal GovernmentsFor-Profit OrganizationsOther (see NOFO for details)Nonprofits without 501(c)(3)County GovernmentsPublic Colleges & UniversitiesSpecial District Governments501(c)(3) NonprofitsPrivate Colleges & UniversitiesIndependent School Districts

Funding Details

Expected Number of Awards: 6
Cost Sharing Required?: No
Funding Instrument: grant

Key Dates

Posted: March 16, 2026

Application Deadline: TBD (0 days remaining)

Agency Contact

Division of Neuroscience and Behavior (DNB) Please contact via e-mail.

NIDA_DNB_BCNB_r61@nih.gov

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