health · HHS-SAMHS-SAMHSA

Medication-Assisted Treatment - Prescription Drug and Opioid Addiction

Substance Abuse and Mental Health Services Adminis · TI-26-008

Closed

Award Range

$0 – $750K

Total Program Funding

$68.3M

Expected Awards

Deadline

July 27, 2026

GRANTQUICK SUMMARYPlain-English Overview

SAMHSA is putting $68.25M into expanding medication-assisted treatment (MAT) for opioid addiction — specifically Medications for Opioid Use Disorder (MOUD) like buprenorphine, methadone, and naltrexone. 91 awards of up to $750K each. The goal is increasing ACCESS to treatment in underserved areas, including rural communities, tribal lands, and communities hit hardest by the opioid crisis. This is one of the largest single SAMHSA grant programs.

Who Should Apply

Community health centers, FQHCs, opioid treatment programs, health departments, tribal health programs, and nonprofits providing or coordinating addiction treatment. Faith-based organizations explicitly eligible.

Who Should NOT Apply

Organizations without capacity to prescribe or coordinate MOUD, individual practitioners, or for-profit entities (nonprofits and public entities only).

Key Requirements (Plain English)

•Must expand access to Medications for Opioid Use Disorder (buprenorphine, methadone, naltrexone)
•Must serve communities with documented opioid crisis impact
•Must be a domestic public or private nonprofit (including faith-based)
•Must demonstrate ability to provide or coordinate evidence-based MAT
•Must track recovery outcomes and reduce overdose deaths

💡 GrantQuick Tip

91 awards means this is one of the least competitive major SAMHSA grants — if you're a community health center or tribal health program in an area with high overdose rates, your odds are excellent. The biggest differentiator: showing you can reach people who currently have NO access to MOUD. Rural areas without a single buprenorphine prescriber, or communities where the nearest methadone clinic is 2+ hours away — that's what SAMHSA is trying to fix.

Competitiveness: Low — 91 awards across the country means most qualified applicants serving underserved areas will be funded. If you're in a high-need area and can prescribe/coordinate MOUD, apply.

What This Grant Funds

The purpose of this program is to expand and enhance access to Medications for Opioid Use Disorder (MOUD), increasing access to treatment and recovery for individuals with Opioid Use Disorder (OUD) and decreasing illicit opioid use, prescription opioid misuse and overdose.

Who Can Apply

Domestic public and private nonprofit entities, including faith-based organizations.

Eligible Applicant Types

Other (see NOFO for details)

Funding Details

Maximum Award: $750K
Total Program Funding: $68.3M
Expected Number of Awards: 91
Cost Sharing Required?: No
Funding Instrument: grant

Key Dates

Posted: July 1, 2026

Application Deadline: July 27, 2026 (0 days remaining)

Agency Contact

Office of Financial Resources Division of Grants Management 240-276-1400

NOFOBudget.CSAT@samhsa.hhs.gov

Ready to apply?

View the full NOFO and submit your application on Grants.gov

View on Grants.gov