health · HHS-SAMHS-SAMHSA

Preventing Drug Overdoses: Community Prevention and Response

Substance Abuse and Mental Health Services Adminis · TI-26-019

Closed

Award Range

$0 – $850K

Total Program Funding

$11.1M

Expected Awards

Deadline

July 27, 2026

GRANTQUICK SUMMARYPlain-English Overview

SAMHSA is giving $11M (13 awards up to $850K each) for community-wide programs to prevent drug overdose deaths — specifically by expanding access to naloxone (Narcan) and other FDA-approved overdose reversal medications. The focus is on COMMUNITY distribution (not just clinical settings): training bystanders, equipping first responders, placing naloxone in libraries/schools/shelters, and building leave-behind programs.

Who Should Apply

Community health organizations, public health departments, harm reduction organizations, faith-based organizations, EMS agencies, or nonprofits working directly with people at risk of overdose. Must be domestic nonprofit or public entity.

Who Should NOT Apply

For-profit pharmaceutical companies, clinical research organizations (this is community distribution, not research), or organizations opposed to harm reduction approaches.

Key Requirements (Plain English)

•Must implement a community-wide overdose prevention program
•Must expand access to FDA-approved overdose reversal medications (naloxone)
•Must be a domestic public or private nonprofit (faith-based OK)
•Must demonstrate community need (overdose death data)
•Must train community members in overdose recognition and response

💡 GrantQuick Tip

13 awards is accessible for most communities with documented overdose problems. The strongest applications will show: (1) high local overdose death rates, (2) specific distribution channels (EMS leave-behind, syringe service programs, libraries, homeless shelters), and (3) a plan to reach people who currently have ZERO access to naloxone. Don't just propose "we'll distribute Narcan" — show WHERE and to WHOM.

Competitiveness: Low-moderate — 13 awards for communities experiencing overdose crises. Most qualified harm reduction or public health orgs in high-need areas will be competitive.

What This Grant Funds

The purpose of this program is to develop and implement a community-wide prevention program to prevent and reduce drug overdose deaths by expanding access to FDA-approved opioid overdose reversal medications.

Who Can Apply

Domestic public and private nonprofit entities, including faith-based organizations.

Eligible Applicant Types

Other (see NOFO for details)

Funding Details

Maximum Award: $850K
Total Program Funding: $11.1M
Expected Number of Awards: 13
Cost Sharing Required?: No
Funding Instrument: grant

Key Dates

Posted: July 1, 2026

Application Deadline: July 27, 2026 (0 days remaining)

Agency Contact

Office of Financial Resources Division of Grants Management 240-276-1400

NOFOBudget.CSAP@samhsa.hhs.gov

Ready to apply?

View the full NOFO and submit your application on Grants.gov

View on Grants.gov