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health · HHS-NIH11

Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)

National Institutes of Health · PAR-27-039

Closed

Deadline

TBD

GRANTQUICK SUMMARYPlain-English Overview

Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional). National Institutes of Health. The National Institutes of Health (NIH) and Centers for Disease Control and Prevention (CDC), including the participating Institutes, Centers and Offices, intend to publish a Notice of Funding Opportunity (NOFO) to invite eligible United States small business concerns (SBCs) to submit Small... Funding amounts not specified.

Who Should Apply

Small businesses

Who Should NOT Apply

Individuals and organizations outside the specified eligible types

Key Requirements (Plain English)

  • Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir

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What This Grant Funds

The National Institutes of Health (NIH) and Centers for Disease Control and Prevention (CDC), including the participating Institutes, Centers and Offices, intend to publish a Notice of Funding Opportunity (NOFO) to invite eligible United States small business concerns (SBCs) to submit Small Business Innovation Research (SBIR) Phase I, and Fast-Track (NIH only) grant applications for the Small Business Transition Grant. Through this NOFO, NIH and CDC will support early-career scientists as they transition into entrepreneurship. In addition to funding research and development efforts at the SBC, a major component of this NOFO is entrepreneurial training, mentoring, and career development of the PD/PI.

Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop responsive projects, including identification of complementary industry mentors and career development resources. This NOFO will utilize the R43/R44 activity code. United States small businesses that have the research capabilities and technological expertise to contribute to the R&D mission(s) of the NIH and CDC awarding components identified in this NOFO are encouraged to begin to consider applying for this new NOFO. This opportunity is available to first-time Principal Investigators, and key personnel must include a mentor with measurable effort committed to the project. 

Who Can Apply

Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity. Individuals are eligible to serve as the PD/PI if they have never been an independent PD/PI on an NIH or CDC research, or corresponding non-NIH peer-reviewed research grant, and are a U.S. Citizen or Lawful Permanent Resident.

Eligible Applicant Types

Small Businesses

Funding Details

Cost Sharing Required?
No
Funding Instrument
grant

Key Dates

Posted: May 27, 2026
Application Deadline: TBD (0 days remaining)

Agency Contact

NIH SEED (Small business Education and Entrepreneurial Development) Office of Extramural Research (OER) 301-827-8595

SEEDinfo@nih.gov

Ready to apply?

View the full NOFO and submit your application on Grants.gov