Autism Single Investigator Innovation Program (Autism-SIIP) – Autism Longitudinal Data Project (ALDP)

The HRSA-22-086: ALDP supports the implementation and completion of research that leverages existing longitudinal data resources and evaluates the effect of early interventions using observational studies/secondary data to improve our understanding of the early life origins, signs, and indicators of ASD/DD and its comorbidities. Applicants to the HRSA-22-086: ALDP will conduct research on topics of interest to HRSA’s Maternal and Child Health Bureau (MCHB), including studies that build on our current knowledge base and leverage existing longitudinal data analyses to: • Study genetic and environmental maternal and perinatal contributing and/or predictive factors for ASD/DD; • Consider physical and behavioral trajectories of ASD/DD and assessment at different stages of life course development; • Explore primary prevention of ASD/DD; Study the effects of various ASD/DD interventions using observational studies/secondary data; and • Promote greater national and public awareness of the early life origins, signs, indicators, and interventions for ASD/DD and its comorbidities by providing leadership in the dissemination of findings from ALDP research.