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health · HHS-NIH11

The Experimental Therapeutics Clinical Trials Network (ETCTN) Lead Academic Organizations (UM1 Clinical Trial Required)

National Institutes of Health · RFA-CA-27-016

Closed

Total Program Funding

$11.8M

Expected Awards

6

Deadline

June 30, 2026

GRANTQUICK SUMMARYPlain-English Overview

The Experimental Therapeutics Clinical Trials Network (ETCTN) Lead Academic Organizations (UM1 Clinical Trial Required). National Institutes of Health. Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications from institutions/organizations that propose to maintain or establish Lead Academic Organizations (LAOs) as part of the NCI Experimental Therapeutics Clinical Trials Network (ETCTN). ETCTN... $11,800,000 total program funding; ~6 awards expected.

Who Should Apply

Other eligible entities, State governments, Other Native American Tribal Organizations, Independent school districts, For-profit organizations (+10 more)

Who Should NOT Apply

Organizations not matching the eligible applicant types listed above

Key Requirements (Plain English)

  • Refer to Section III
  • Deadline: 2026-06-30

💡 GrantQuick Tip

High-value award — invest significantly in proposal quality. Consider hiring a grant writer.

Competitiveness: High — limited number of awards

What This Grant Funds

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications from institutions/organizations that propose to maintain or establish Lead Academic Organizations (LAOs) as part of the NCI Experimental Therapeutics Clinical Trials Network (ETCTN). ETCTN LAOs will design, develop, monitor, conduct, and analyze early phase clinical trials (e.g., phase 0, phase 1, phase 2, pilot, and other experimental therapeutic clinical trials) involving agents under regulatory sponsorship for New Investigational Drug (IND) applications held by NCI's Division of Cancer Treatment and Diagnosis (DCTD), Cancer Therapy Evaluation Program (CTEP). Each ETCTN LAO will participate in clinical trials it leads as well as clinical trials led by other LAOs in the network.

Attachments

Who Can Apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Eligible institution/organization for the purposes of this application is defined as an academic center/organization in the United States or Canada providing direct medical care to patients that is considered one integral organizational entity under a single financial management system and governance structure. A center/organization (e.g., an academic hospital and/or academic clinic program) for this application is distinguished from large medical centers whose primary mission is patient care. In addition to patient care, academic centers/organizations have comprehensive medical training programs, investigational pharmacies, advanced imaging facilities, and preclinical laboratories that perform basic research.The only Non-domestic (non-U.S.) Entities (Foreign Institutions) allowed in response to this NOFO are Canadian Institutions.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Eligible Applicant Types

Other (see NOFO for details)State GovernmentsOther Tribal OrganizationsIndependent School DistrictsFor-Profit OrganizationsFederally Recognized Tribal GovernmentsPrivate Colleges & UniversitiesSpecial District GovernmentsSmall BusinessesCounty GovernmentsPublic And Indian Housing AuthoritiesNonprofits without 501(c)(3)501(c)(3) NonprofitsPublic Colleges & UniversitiesCity/Township Governments

Funding Details

Total Program Funding
$11.8M
Expected Number of Awards
6
Cost Sharing Required?
No
Funding Instrument
cooperative_agreement

Key Dates

Posted: May 8, 2026
Application Deadline: June 30, 2026 (0 days remaining)

Agency Contact

NCI ETCTN RFA Email: NCIETCTNRFA@mail.nih.gov

Email: NCIETCTNRFA@mail.nih.gov

Ready to apply?

View the full NOFO and submit your application on Grants.gov