health · HHS-NIH11

New Generation of Glucose Control Technologies Incorporating AI/ML Tools/Strategies (R01 - Clinical Trial Optional)

National Institutes of Health · RFA-DK-27-146

Closed

Award Range

$0 – $500K

Total Program Funding

$3.0M

Expected Awards

Deadline

June 17, 2026

GRANTQUICK SUMMARYPlain-English Overview

New Generation of Glucose Control Technologies Incorporating AI/ML Tools/Strategies (R01 - Clinical Trial Optional). National Institutes of Health. The purpose of this funding opportunity is to support research addressing barriers that limit progress toward more effective open- and closed-loop diabetes control systems. This may include research that addresses: 1) innovation of sensing relevant analytes/physiologic signals; 2) novel formulation... up to $500,000 per award; $3,000,000 total program funding; ~5 awards expected.

Who Should Apply

Public And Indian Housing Authorities, Federally Recognized Native American Tribal Governments, Small businesses, State governments, City/township governments (+10 more)

Who Should NOT Apply

Organizations not matching the eligible applicant types listed above

Key Requirements (Plain English)

•Refer to Section III
•Deadline: 2026-06-17

💡 GrantQuick Tip

High-value award — invest significantly in proposal quality. Consider hiring a grant writer.

Competitiveness: Very high — extremely limited awards available

What This Grant Funds

The purpose of this funding opportunity is to support research addressing barriers that limit progress toward more effective open- and closed-loop diabetes control systems. This may include research that addresses: 1) innovation of sensing relevant analytes/physiologic signals; 2) novel formulation and delivery of hormones; 3) artificial intelligence (AI)/machine learning (ML)-driven tools/algorithms; and 4) digital twin modeling to augment decision support and automated control systems with the goal of improving glycemic control, reducing burden of care, and enhancing quality of life of people with T1D].This NOFO is associated with the Special Diabetes Program (https://www.niddk.nih.gov/about-niddk/research-areas/diabetes/type-1-diabetes-special-statutory-funding-program/about-special-diabetes-program) which funds research on the prevention, treatment, and cure of type 1 diabetes and its complications, including unique, innovative, and collaborative research consortia and clinical trials networks

Attachments

PDF

RFA-DK-27-146-Full-Announcement.html

Who Can Apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Eligible Applicant Types

Public And Indian Housing AuthoritiesFederally Recognized Tribal GovernmentsSmall BusinessesState GovernmentsCity/Township GovernmentsOther Tribal OrganizationsSpecial District GovernmentsCounty GovernmentsNonprofits without 501(c)(3)For-Profit Organizations501(c)(3) NonprofitsPublic Colleges & UniversitiesPrivate Colleges & UniversitiesIndependent School DistrictsOther (see NOFO for details)

Funding Details

Maximum Award: $500K
Total Program Funding: $3.0M
Expected Number of Awards: 5
Cost Sharing Required?: No
Funding Instrument: grant

Key Dates

Posted: May 7, 2026

Application Deadline: June 17, 2026 (0 days remaining)

Agency Contact

Division of Diabetes, Endocrinology and Metabolic Diseases NIDDK_DEM@nih.gov

NIDDK_DEM@nih.gov

Ready to apply?

View the full NOFO and submit your application on Grants.gov

View on Grants.gov