Opioid Prevention Grants

The federal government funds opioid programs through competitive grants posted on Grants.gov. Eligible applicants typically include 501(c)(3) nonprofits, state/local governments, tribal organizations, and educational institutions. Applications usually require a project narrative, budget justification, and evidence of organizational capacity. New opportunities post year-round with 30-60 day application windows.

Opioid Prevention Grants

Limited Competition: Institutional Development Award (IDeA) for Clinical &amp; Translational Research (CTR) (P30 - CT Optional)

Limited Competition: Centers of Biomedical Research Excellence: Development Phase (COBRE-D) (P30 - Clinical Trial Not Allowed)

BJA FY 2026 Comprehensive Opioid, Stimulant, and Substance Use Site-Based Program

BJA FY 2026 Harold Rogers Prescription Drug Monitoring Program

FY 2026 DRUG COURT TRAINING AND TECHNICAL ASSISTANCE COMPETITIVE COOPERATIVE AGREEMENT SOLICITATION

PRIMED-AI: Data-to-Model Academic-Industrial Partnerships (D2M-AIP) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (UG3/UH3 Clinical Trial Optional)

Model-to-Clinic (M2C) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (UG3/UH3, Clinical Trial Optional)

Validation Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U54 Clinical Trials Not Allowed)

Logistics Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U24 Clinical Trials Not Allowed)

Development and Testing of a Multi-use Frameworks Playbook for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U01 Clinical Trial Not Allowed)

Single Source: Post-Stroke Vascular Contributions to Cognitive Impairment and Dementia (VCID) in the United States (U19 - Clinical Trial Not Allowed)

Nutrition Obesity Research Centers (NORCs) (P30 Clinical Trial Optional)

NIH Director&rsquo;s Transformative Research Award for Individual and Group Science (R01 Clinical Trial Optional)

NIH Director&rsquo;s Pioneer Award (DP1 Clinical Trial Optional)

Atopic Dermatitis Research Network (ADRN) (U19 Clinical Trial Optional)

Renewal of the Clinician-Scientists Transdisciplinary Aging Research (Clin-STAR) Coordinating Center (U24 Clinical Trial Not Allowed)

NIH Director&rsquo;s Early Independence Award (DP5 Clinical Trial Optional)

Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)

Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)

Limited Competition: Growing Great Ideas: Research Education Course in Entrepreneurship and Product Development for Researchers Studying Drug Use, Drug Misuse, and Drug Addiction (UE5 Clinical Trial Not Allowed)

Institutional Mentored Career Development Award (Parent K12) (Clinical Trials Not Allowed)

Limited Competition: Centers of Biomedical Research Excellence: Expansion/Sustainability Phases (COBRE-E/S) (P30 - Clinical Trial Not Allowed)

GREGoRi Technology Integration Center (U01, Clinical Trials Optional)

Discovery of the Genetic Basis of Childhood Cancers and of Congenital Anomalies: Gabriella Miller Kids First Pediatric Research Program (X01 Clinical Trial Not Allowed)

GREGoRi Innovation Projects (U01 Clinical Trial Optional)

About Opioid Prevention Grants

Limited Competition: Institutional Development Award (IDeA) for Clinical & Translational Research (CTR) (P30 - CT Optional)

NIH Director’s Transformative Research Award for Individual and Group Science (R01 Clinical Trial Optional)

NIH Director’s Pioneer Award (DP1 Clinical Trial Optional)

NIH Director’s Early Independence Award (DP5 Clinical Trial Optional)