Opioid Prevention Grants

The federal government funds opioid programs through competitive grants posted on Grants.gov. Eligible applicants typically include 501(c)(3) nonprofits, state/local governments, tribal organizations, and educational institutions. Applications usually require a project narrative, budget justification, and evidence of organizational capacity. New opportunities post year-round with 30-60 day application windows.

Opioid Prevention Grants

Research Centers in Minority Institutions (RCMI) Coordinating Center (U24 - Clinical Trial Optional)

FY26 Community Policing Development (CPD) Microgrants

Preventing Drug Overdoses: Community Prevention and Response

First Responders-Comprehensive Addiction and Recovery Act

Emergency Department Alternatives to Opioids Program

Medication-Assisted Treatment - Prescription Drug and Opioid Addiction

PRIMED-AI: Data-to-Model Academic-Industrial Partnerships (D2M-AIP) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (UG3/UH3 Clinical Trial Optional)

Model-to-Clinic (M2C) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (UG3/UH3, Clinical Trial Optional)

Validation Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U54 Clinical Trials Not Allowed)

Logistics Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U24 Clinical Trials Not Allowed)

Development and Testing of a Multi-use Frameworks Playbook for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U01 Clinical Trial Not Allowed)

Single Source: Post-Stroke Vascular Contributions to Cognitive Impairment and Dementia (VCID) in the United States (U19 - Clinical Trial Not Allowed)

Nutrition Obesity Research Centers (NORCs) (P30 Clinical Trial Optional)

NIH Director&rsquo;s Transformative Research Award for Individual and Group Science (R01 Clinical Trial Optional)

NIH Director&rsquo;s Pioneer Award (DP1 Clinical Trial Optional)

Atopic Dermatitis Research Network (ADRN) (U19 Clinical Trial Optional)

&#8203;Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities&#8203;

Renewal of the Clinician-Scientists Transdisciplinary Aging Research (Clin-STAR) Coordinating Center (U24 Clinical Trial Not Allowed)

NIH Director&rsquo;s New Innovator Award (DP2 Clinical Trial Optional)

NIH Director&rsquo;s Early Independence Award (DP5 Clinical Trial Optional)

Rural Communities Opioid Response Program (RCORP)-Technical Assistance

Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)

Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)

Limited Competition: Growing Great Ideas: Research Education Course in Entrepreneurship and Product Development for Researchers Studying Drug Use, Drug Misuse, and Drug Addiction (UE5 Clinical Trial Not Allowed)

Institutional Mentored Career Development Award (Parent K12) (Clinical Trials Not Allowed)

About Opioid Prevention Grants

NIH Director’s Transformative Research Award for Individual and Group Science (R01 Clinical Trial Optional)

NIH Director’s Pioneer Award (DP1 Clinical Trial Optional)

Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities

NIH Director’s New Innovator Award (DP2 Clinical Trial Optional)

NIH Director’s Early Independence Award (DP5 Clinical Trial Optional)